On the evening of Tuesday, March 19, 2002, a father returned home from work to his residence in the 4600 block of East 15th Street in Long Beach, California. What he walked into inside the family bathroom was an unimaginable domestic tragedy. Lying unconscious on the floor were his 15-month-old daughter, Isabella Dora Sanford, and his 29-year-old wife, Angelica Sanford. Angelica had slashed her wrists and appeared to have taken a severe overdose of medication or illicit drugs. Nearby, the little girl was completely unresponsive.
Emergency medical personnel rushed both the toddler and her mother from the East 15th Street residence to St. Mary Medical Center. Despite the efforts of emergency room physicians, Isabella Dora Sanford, a Latina infant, was pronounced dead shortly after her arrival. Angelica Sanford survived the immediate crisis but fell into a deep coma, with medical staff noting that the substances she ingested had potentially inflicted permanent and severe brain damage.
Long Beach Police Department homicide investigators were dispatched to the hospital and the home to process the scene. Homicide Officer David Marander noted that while the cause of the child's death was not immediately obvious, the circumstances pointed directly to an apparent murder and attempted suicide. Later medical examiner findings determined Isabella died from probable asphyxia, with ketamine exposure listed as a significant contributing condition. Officer Marander remarked to reporters that charges against Angelica would depend on whether she ever emerged from her comatose state. In the days following the event, the investigator candidly acknowledged that there remained quite a bit about the incident that authorities simply did not know.
In the surrounding neighborhood along East 15th Street, neighbors and acquaintances were left stunned by the sudden violence. The residential street sat in a quiet pocket of Long Beach where families generally knew one another in passing. In the days following the child's death, neighbors created an impromptu memorial of flowers and candles outside the Sanford home, with several mentioning they had often seen the young mother and baby together and had never noticed any warning signs of turmoil or distress.
The year 2002 saw violent crime and domestic homicides claim dozens of lives across Long Beach and the broader Los Angeles County basin, but cases involving the loss of a toddler within the confines of a family home left a uniquely painful mark on the community. Long Beach police urged anyone who might have had insight into the family's situation or the events leading up to that evening to contact the department's homicide detail.
Decades have elapsed since Isabella was pronounced dead at the hospital. With her mother critically incapacitated and comatose following the incident, no public records of an arrest, formal criminal prosecution, or conviction ever followed. The investigation effectively stalled behind hospital doors and lingering medical uncertainties. Today, Isabella's death officially remains an open and unresolved homicide on county records, an enduring tragedy on a quiet suburban street that has never reached legal closure.