On the evening of December 13, 2018, Melissa Peskey, a 40-year-old woman, was traveling with her two young children, ages 5 and 11, on Interstate 70 near Boonville, Missouri. The family was over 450 miles from their home in Hartford, South Dakota, on what was described as a road trip to visit a friend before the Christmas holiday. At approximately 10:30 PM, their vehicle veered into the median and crashed. While the children were not physically harmed in the incident, Melissa was found deceased in the driver's seat.
Initially, authorities treated the incident as a fatal car accident. However, an autopsy soon revealed a more sinister cause of death: Melissa had sustained a fatal gunshot wound fired from outside the vehicle. This discovery shifted the focus of the investigation to a homicide, with investigators coming to believe that she was deliberately targeted. The Missouri State Highway Patrol launched an extensive investigation, following up on hundreds of leads, but struggled to identify a suspect with little to no witnesses to the crime.
In the wake of Melissa's death, public speculation arose concerning her husband, Ryan Peskey. A friend of Melissa's revealed that Melissa had asked her husband for a divorce shortly before he was deployed with the South Dakota National Guard and had expressed being 'terrified' of his return. Ryan Peskey himself stated that authorities had informed him he was a person of interest in the case, though law enforcement has never publicly named any suspects. The investigation also brought to light a dispute over Melissa's life insurance policies.
Despite the passage of years and a reward offered for information, no arrests have been made in connection with Melissa Peskey's murder, and the case remains unsolved. Investigators have stated that it is an active case and not considered cold, and they believe they have more information than has been publicly released. Ryan Peskey has maintained his innocence and has reportedly been advised not to comment on the ongoing investigation. The case has been the subject of true crime podcasts and news reports, keeping the memory of the unsolved roadside murder alive.